// Andril Case Study - GLOBAL CONFIGURATIONS // author: Marko Laakso, Riku Louhimo // Enables gene expression analysis doGeneExpression = true // Enables transcript expression analysis doTranscriptExpression = true // Enables microRNA expression analysis doMiRNAExpression = true // Enables copy number analysis doArrayCGH = true /* Anduril installation */ andurilHome = $ANDURIL_HOME // Root of the project data storage //dataDir = "/storageExt/tcga-glioblastoma" dataDir = "data" // Gene expression data // NOTE: The second and the last lines of this file were removed manually. prenormalizedGeneExpression = dataDir+"/expression/Expression-Genes/BI__HT_HG-U133A/Level_2/broad.mit.edu__HT_HG-U133A__probeset_rma" /** Transcript expression matrix */ transcriptExpressionFileName = dataDir+"/exon-normalized/Expression-Exon/LBL_HuEx-1_0-st-v2/Level_2/TranscriptExpression_v56" /** Gene level transcript expression matrix */ genelevelExpressionFileName = dataDir+"/exon-normalized/Expression-Exon/LBL_HuEx-1_0-st-v2/Level_2/GeneExpression_v56" /** Array CGH data */ arrayCGHdatadir = dataDir+"/acgh/acgh-data/cangem/DataFiles/" /** Annotation file for transcript expression matrix */ transcriptAnnotationFileName = dataDir+"/exon-normalized/Expression-Exon/LBL_HuEx-1_0-st-v2/Level_2/TranscriptExprAnnotation_v56" /** Clinical parameters for the patients */ patientMetadataFileName = dataDir+"/patient-metadata.csv" /** Database configurations for Ensemble database~\cite{flicek2008}. The exact content can be seen in Section~\ref{propertiesDoc}. */ ensembl = INPUT(path="ensemblHS.properties") /** Database configuration for Ensembl variation database. */ snpdb = INPUT(path="ensemblSNP.properties") /** Settings for SNPHelistin database (see Section~\ref{propertiesDoc}) */ genotypeDB = INPUT(path="csv/snpstorage.properties") miRNAExprNormalized = INPUT(path=dataDir+"/mirna/Expression-miRNA/UNC__H-miRNA_8x15K/Level_2/unc.edu__H-miRNA_8x15K__Quantile_Normalized_Log2") miRNAProbeAnnot = INPUT(path=dataDir+"/mirna/agilent_G4470A_probes_CIBEX.csv") miRNANames = INPUT(path=dataDir+"/mirna/miRBase_Sequences_rel9.1.csv") miRNATargets = INPUT(path=dataDir+"/mirna/miRBase_Targets_v4_hsa.csv") /** A very short description of this study */ abstract = INPUT(path="abstract") authors = "Kristian Ovaska,Marko Laakso,Riku Louhimo,Erkka Valo,Viljami Aittom\\\"aki,Sampsa Hautaniemi"