Main pageKEGG pathway → Protein export

KEGG pathway: Protein export

Pathway hsa03060
Name Protein export
Members SEC61A1 SEC61B SEC61G HSPA5 SEC11A OXA1L SRPRB IMMP2L SRP54 SRP14 SRP72 IMMP1L SPCS1 SRPR SRP9 SEC63 SRP19 SPCS3 SEC11C SPCS2 SRP68 SEC62 SEC61A2
Description The protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the general protein export system that transports newly synthesized proteins into or across the cell membrane. The translocation channel is formed from a conserved trimeric membrane protein complex, called the Sec61/SecY complex. The twin-arginine translocation (Tat) pathway is another protein transport system that transports folded proteins in bacteria, archaea, and chloroplasts. Many Tat systems comprise three functionally different membrane proteins, TatA, TatB, and TatC, but TatA and TatE seem to have overlapping functions, with TatA having by far the more important role.