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Attributes in Gene

Field Description Color range
GeneName HUGO gene name
GeneID Ensembl gene id
GeneExpression: foldchange Average gene expression fold change Underexpression (0.13) Neutral (1.0) Overexpression (8.0)
GeneExpression: p-value P-value associated with gene expression. Not significant (1.0) 0.063 Significant (0.0039)
GeneExpression: survival Minimum p-value for survival-affecting differentially expressed genes based on Kaplan-Meier analysis with logrank test. Survival analysis has been conducted for differentially expressed genes only. Not significant (1.0) 0.00017 Significant (3.0e-08)
SNPSurvival: p-value Minimum p-value for survival-affecting SNPs of this gene, based on Kaplan-Meier analysis. Not significant (1.0) 0.00017 Significant (3.0e-08)
DNABand Chromosomal location of the gene.
Protein Interactions UniProt ID; external links show protein-protein interactions in PINA
GeneDesc Description of the gene.
Aliases Possible alternate names for the gene.
TranscriptExpression:Min Minimum splice variant expression for all splice variants of the gene present on Affymetrix exon microarrays. Underexpression (0.13) Neutral (1.0) Overexpression (8.0)
TranscriptExpression:Max Maximum splice variant expression for all splice variants of the gene present on Affymetrix exon microarrays. Underexpression (0.13) Neutral (1.0) Overexpression (8.0)
TranscriptExpression:Survival Minimum p-value for survival-affecting differentially expressed splice variants based on Kaplan-Meier analysis with logrank test. Survival analysis has been conducted for differentially expressed transcripts only. Not significant (1.0) 0.00017 Significant (3.0e-08)
CGH Gain: freq The frequency of karyotypic gain that the region containing this gene has been found at in the sample group. -0.30 No gain (0.0) Gain (0.30)
CGH Gain: exp-cor Integration score for the influence of karyotypic gain on transcript expression (p < 0.05). Opposite effect (0.0) None (1.0) Concordant effect (2.0)
CGH Loss: freq The frequency of karyotypic loss that the region containing this gene has been found at in the sample group. -0.30 No loss (0.0) Loss (0.30)
CGH Loss: exp-cor Integration score for the influence of karyotypic loss on transcript expression (p < 0.05). Opposite effect (0.0) None (1.0) Concordant effect (2.0)
CGHSurvival: p-value P-value for survival effect of copy number aberrations in this gene Not significant (1.0) 0.00017 Significant (3.0e-08)
Methylation: M value Median M value of DNA methylation of CpG sites near the gene in tumors. Hypomethylated (0.0) 0.50 Hypermethylated (1.0)
Methylation: M SD Standard deviation of the M values Unmethylated (0.0) 0.50 Methylated (1.0)
Methylation: survival P-value for survival effect of differentially methylated samples. Not significant (1.0) 0.00017 Significant (3.0e-08)
CNAmet: score Score for joint effect of copy number alteration and demethylation on gene expression Opposite effect (0.0) 0.50 Concordant effect (1.0)